The Ophelia Bus Terminal located in North Quito will take you directly to Mindo. It will cost $3.10 and it is an approximately 2hr trip. During the Summer (busy season) it is recommended to arrive early to buy your tickets.
Mon-Fri
Quito to Mindo: 0800 – 0900 – 1100 – 1300 – 1600
Mindo to Quito: 0630 -1100 – 1345 – 1530 – 1700.
Sat-Sun
Quito to Mindo: 0740 – 0820 – 0920 – 1100 – 1300 – 1400 – 1600
Mindo to Quito: 0630 – 1100 – 1300 – 1400 – 1500 – 1600 – 17w00.
(note that during the pandemic times may have changed, double check departure times with your hostel or hotel before leaving)